Trigun (トライガン, Toraigan^?) is a sci-fi manga series with a steampunk Wild West theme created by Yasuhiro Nightow in 1995, and adapted into a 26 episode anime series in 1998 by Madhouse. It is the story of Vash the Stampede, a.k.a. The Humanoid Typhoon, a person with a $$60,000,000,000 bounty on his head, and the two Bernardelli Insurance Society employees, Meryl Stryfe and Milly Thompson, who were ordered to follow him and minimize the damage that seems to follow Vash everywhere he goes. Like Himura Kenshin from the manga/anime series Rurouni Kenshin, Vash can almost appear to have two personalities — that of a harmless idiot and that of an unstoppable warrior -- but is always staunchly pacifist.

UK anime, manga, and J-Culture magazine, NEO revealed in November 2005 that during an interview with Masao Maruyama, the founder of Madhouse said that he was currently working on a new Trigun movie. Apparently the project will be released "in a couple of years".